SCN3A

GENE INFORMATION

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Gene name

SCN3A (HGNC Symbol)

Synonyms

Nav1.3

Description

sodium channel, voltage-gated, type III, alpha subunit (HGNC Symbol)

Entrez gene summary

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q24.3

Chromosome location (bp)

165944032 - 166060577

Ensembl

ENSG00000153253 (version 73.37)

Entrez gene

6328

UniProt

Q9NY46 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NY46

Antibodypedia

SCN3A antibodies
 

PROTEIN VIEW

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SCN3A-001
 
SCN3A-002
 
SCN3A-003
 
SCN3A-004
 
SCN3A-201
 
SCN3A-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SCN3A-001 ENSP00000283254
ENST00000283254
Q9NY46
Show all »
Show » Show » 2000 226.3 No >9
SCN3A-002 ENSP00000386726
ENST00000409101
Q9NY46
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Show » Show » 1951 221.5 No >9
SCN3A-003 ENSP00000391569
ENST00000453007
C9JBM7
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Show » Show » 200 22.9 No 1
SCN3A-004 ENSP00000403348
ENST00000440431
E7EUE6
Show all »
Show » Show » 1364 154.5 No >9
SCN3A-201 ENSP00000353206
ENST00000360093
Q9NY46
Show all »
Show » Show » 2000 226.3 No >9
SCN3A-202 ENSP00000439920
ENST00000540861
F5H4V8
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Show » Show » 483 54.8 No 7