ING1

GENE INFORMATION

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Gene name

ING1 (HGNC Symbol)

Synonyms

p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a

Description

Inhibitor of growth family, member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Chromosome

13

Cytoband

q34

Chromosome location (bp)

111365083 - 111373421

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000153487 (version 75.37)

Entrez gene

3621

UniProt

Q9UK53 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UK53

Antibodypedia

ING1 antibodies
 

PROTEIN VIEW

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ING1-001
 
ING1-002
 
ING1-003
 
ING1-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ING1-001 ENSP00000328436
ENST00000333219
Q9UK53
Show all »
Show » Show » 279 31.9 No 0
ING1-002 ENSP00000364930
ENST00000375775
Q9UK53
Show all »
Show » Show » 210 23.7 No 0
ING1-003 ENSP00000345202
ENST00000338450
Q9UK53
Show all »
Show » Show » 235 26.8 No 0
ING1-004 ENSP00000364929
ENST00000375774
Q9UK53
Show all »
Show » Show » 422 46.7 No 0