CACNA2D1

GENE INFORMATION

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Gene name

CACNA2D1 (HGNC Symbol)

Synonyms

CACNA2, CACNL2A, LINC01112, lncRNA-N3, MHS3

Description

Calcium channel, voltage-dependent, alpha 2/delta subunit 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q21.11

Chromosome location (bp)

81575760 - 82073114

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000153956 (version 75.37)

Entrez gene

781

UniProt

P54289 (UniProt - Evidence at protein level)

neXtProt

NX_P54289

Antibodypedia

CACNA2D1 antibodies
 

PROTEIN VIEW

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CACNA2D1-001
 
CACNA2D1-002
 
CACNA2D1-005
 
CACNA2D1-201
 
CACNA2D1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CACNA2D1-001 ENSP00000349320
ENST00000356860
P54289
Show all »
Show » Show » 1091 123.2 Yes 1
CACNA2D1-002 ENSP00000405395
ENST00000423588
E7ERK3
Show all »
Show » 309 34.6 Yes 0
CACNA2D1-005 ENSP00000409374
ENST00000443883
Show » 280 32.4 No 0
CACNA2D1-201 ENSP00000348589
ENST00000356253
P54289
Show all »
Show » Show » 1103 124.6 Yes 1
CACNA2D1-202 ENSP00000443124
ENST00000535308
B7Z658
Show all »
Show » 303 33.8 No 1