GRAP

CANCER ATLAS

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Gene description

GRB2-related adaptor protein

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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HPA046595
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Occasional cases of prostate and liver cancer displayed strong cytoplasmic staining. Moderate cytoplasmic positivity with occasional nuclear staining was observed in a few cases of malignant lymphomas, malignant melanomas, thyroid, testis, lung and ovarian cancers. Remaining malignant cells were weakly stained or negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected