Fields »

SUBCELLULAR LOCATION

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Main location(s)

Nucleus but not nucleoli

Additional location(s)

Cytoplasm 

Staining summary

Mainly localized to the nucleus but also to the cytoplasm.

Reliability (APE)

Low

Antibodies in assay

HPA006092, HPA024356
 

Antibody HPA006092

 

Antibody HPA024356

 

         Cell line A-431

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Location(s)

Nucleus but not nucleoli, Cytoplasm  

Staining characteristics

Granular  

Staining intensity

Moderate Negative 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Nucleus but not nucleoli  

Staining characteristics

Granular  

Staining intensity

Weak Negative 

Validation

One/multiple location(s) with no available experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-251MG shows positivity in nucleus but not nucleoli.
 

Immunofluorescent staining of human cell line A-431 shows no positivity.
 

Summary

Staining of nucleus in U-251 MG and A-431 with additional staining of cytoplasm in A-431.   No staining was observed in any of the three cell lines.  

Validation

The subcellular location is partly supported by literature or no literature is available.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Cytoplasm
Nucleus but not nucleoli