ABCA5

GENE INFORMATION

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Gene name

ABCA5 (HGNC Symbol)

Synonyms

EST90625

Description

ATP-binding cassette, sub-family A (ABC1), member 5 (HGNC Symbol)

Entrez gene summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q24.3

Chromosome location (bp)

69244311 - 69327244

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154265 (version 78.38)

Entrez gene

23461

UniProt

Q8WWZ7 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8WWZ7

Antibodypedia

ABCA5 antibodies
 

PROTEIN VIEW

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ABCA5-001
 
ABCA5-003
 
ABCA5-004
 
ABCA5-008
 
ABCA5-009
 
ABCA5-011
 
ABCA5-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCA5-001 ENSP00000376443
ENST00000392676
Q8WWZ7
Show all »
Show » Show » 1642 186.5 No >9
ABCA5-003 ENSP00000467448
ENST00000593153
K7EPM3
Show all »
Show » Show » 917 103.6 No 9
ABCA5-004 ENSP00000467882
ENST00000588877
Q8WWZ7
Show all »
Show » Show » 1642 186.5 No >9
ABCA5-008 ENSP00000465351
ENST00000586811
K7EJW6
Show all »
Show » Show » 574 65.6 No 5
ABCA5-009 ENSP00000467672
ENST00000588665
K7EQ50
Show all »
Show » 38 4.5 No 0
ABCA5-011 ENSP00000466662
ENST00000592568
K7EMV2
Show all »
Show » 127 14.8 No 1
ABCA5-012 ENSP00000466931
ENST00000589975
Show » 192 21.4 No 3