UCHL1

GENE INFORMATION

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Gene name

UCHL1 (HGNC Symbol)

Synonyms

PARK5, PGP9.5, Uch-L1

Description

ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]

Chromosome

4 (Chromosome progress)

Cytoband

p13

Chromosome location (bp)

41258430 - 41270472

Ensembl

ENSG00000154277 (version 73.37)

Entrez gene

7345

UniProt

P09936 (UniProt - Evidence at protein level)

neXtProt

NX_P09936

Antibodypedia

UCHL1 antibodies
 

PROTEIN VIEW

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UCHL1-001
 
UCHL1-002
 
UCHL1-005
 
UCHL1-007
 
UCHL1-009
 
UCHL1-010
 
UCHL1-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UCHL1-001 ENSP00000284440
ENST00000284440
P09936
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Show » Show » 223 24.8 No 0
UCHL1-002 ENSP00000425714
ENST00000512419
D6RJD9
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69 7.8 No 0
UCHL1-005 ENSP00000422542
ENST00000503431
P09936
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Show » Show » 223 24.8 No 0
UCHL1-007 ENSP00000426634
ENST00000514924
D6RF53
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Show » 58 6.3 No 0
UCHL1-009 ENSP00000426895
ENST00000508768
D6RE83
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Show » 207 23.2 No 0
UCHL1-010 ENSP00000423348
ENST00000505232
D6R974
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Show » 156 17.4 No 0
UCHL1-012 ENSP00000423623
ENST00000512788
D6R956
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Show » 241 26.8 No 0