CXADR

GENERAL INFORMATION

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Gene name

CXADR

Gene description

Coxsackie virus and adenovirus receptor

Protein class

Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Membranous and cytoplasmic expression at variable levels in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data. Caution, targets protein from more than one gene.

Data reliability

Supportive based on 4 antibodies.
HPA003342 , HPA030411 , HPA030412 , CAB005103
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

CXADR (HGNC Symbol)

Synonyms

CAR

Description

Coxsackie virus and adenovirus receptor (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. [provided by RefSeq, May 2011]

Chromosome

21

Cytoband

q21.1

Chromosome location (bp)

17512382 - 17593579

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154639 (version 78.38)

Entrez gene

1525

UniProt

P78310 (UniProt - Evidence at protein level)

neXtProt

NX_P78310

Antibodypedia

CXADR antibodies


PROTEIN BROWSER

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ENST00000284878
 
ENST00000356275
 
ENST00000400165
 
ENST00000400166
 
ENST00000400169
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CXADR-001 ENSP00000284878
ENST00000284878
P78310
Show all »
Show » Show » 365 40 Yes 1
CXADR-002 ENSP00000383033
ENST00000400169
P78310
Show all »
Show » Show » 352 38.9 Yes 1
CXADR-003 ENSP00000383030
ENST00000400166
P78310
Show all »
Show » Show » 252 28.2 Yes 0
CXADR-004 ENSP00000383029
ENST00000400165
P78310
Show all »
Show » Show » 200 22.4 Yes 0
CXADR-005 ENSP00000348620
ENST00000356275
P78310
Show all »
Show » Show » 89 10 Yes 0