TMPRSS15

GENE INFORMATION

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Gene name

TMPRSS15 (HGNC Symbol)

Synonyms

ENTK, MGC133046, PRSS7

Description

transmembrane protease, serine 15 (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq, Jul 2008]

Chromosome

21 (Chromosome progress)

Cytoband

q21.1

Chromosome location (bp)

19641433 - 19858197

Ensembl

ENSG00000154646 (version 73.37)

Entrez gene

5651

UniProt

P98073 (UniProt - Evidence at protein level)

neXtProt

NX_P98073

Antibodypedia

TMPRSS15 antibodies
 

PROTEIN VIEW

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TMPRSS15-001
 
TMPRSS15-002
 
TMPRSS15-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TMPRSS15-001 ENSP00000284885
ENST00000284885
P98073
Show all »
Show » Show » 1019 112.9 No 0
TMPRSS15-002 ENSP00000398253
ENST00000422787
E9PG70
Show all »
Show » 228 25 No 0
TMPRSS15-003 ENSP00000474811
ENST00000474775
5 0.5 No 0