EPHB1

GENE INFORMATION

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Gene name

EPHB1 (HGNC Symbol)

Synonyms

EPHT2, Hek6

Description

EPH receptor B1 (HGNC Symbol)

Entrez gene summary

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q22.2

Chromosome location (bp)

134316643 - 134979309

Ensembl

ENSG00000154928 (version 73.37)

Entrez gene

2047

UniProt

P54762 (UniProt - Evidence at protein level)

neXtProt

NX_P54762

Antibodypedia

EPHB1 antibodies
 

PROTEIN VIEW

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EPHB1-004
 
EPHB1-005
 
EPHB1-006
 
EPHB1-007
 
EPHB1-011
 
EPHB1-012
 
EPHB1-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHB1-004 ENSP00000417435
ENST00000460895
C9JB88
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Show » 113 13 No 0
EPHB1-005 ENSP00000381097
ENST00000398015
P54762
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Show » Show » 984 109.9 Yes 1
EPHB1-006 ENSP00000419574
ENST00000493838
B3KTB2
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Show » Show » 545 61.4 No 1
EPHB1-007 ENSP00000420338
ENST00000482618
F8WDG5
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Show » Show » 281 31.6 Yes 0
EPHB1-011 ENSP00000418352
ENST00000474732
C9J6S4
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Show » 150 17.1 No 0
EPHB1-012 ENSP00000419688
ENST00000497173
C9K090
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Show » 42 4.7 No 0
EPHB1-013 ENSP00000417216
ENST00000473867
C9J466
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Show » 102 11.8 No 0