MARCKS

GENE INFORMATION

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Gene name

MARCKS (HGNC Symbol)

Synonyms

80K-L, MACS, PKCSL

Description

myristoylated alanine-rich protein kinase C substrate (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]

Chromosome

6 (Chromosome progress)

Cytoband

q21

Chromosome location (bp)

114178541 - 114184648

Ensembl

ENSG00000155130 (version 73.37)

Entrez gene

4082

UniProt

P29966 (UniProt - Evidence at protein level)

neXtProt

NX_P29966

Antibodypedia

MARCKS antibodies
 

PROTEIN VIEW

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MARCKS-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MARCKS-001 ENSP00000357624
ENST00000368635
P29966
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