USP25

GENE INFORMATION

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Gene name

USP25 (HGNC Symbol)

Synonyms

USP21

Description

ubiquitin specific peptidase 25 (HGNC Symbol)

Entrez gene summary

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).[supplied by OMIM, Mar 2008]

Chromosome

21 (Chromosome progress)

Cytoband

q21.1

Chromosome location (bp)

17102344 - 17252377

Ensembl

ENSG00000155313 (version 73.37)

Entrez gene

29761

UniProt

Q9UHP3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHP3

Antibodypedia

USP25 antibodies
 

PROTEIN VIEW

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USP25-001
 
USP25-002
 
USP25-003
 
USP25-005
 
USP25-006
 
USP25-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

USP25-001 ENSP00000285681
ENST00000285681
Q9UHP3
Show all »
Show » Show » 1087 125.7 No 0
USP25-002 ENSP00000285679
ENST00000285679
Q9UHP3
Show all »
Show » Show » 1055 122.2 No 0
USP25-003 ENSP00000299574
ENST00000351097
Q96B65
Show all »
Show » Show » 450 52.2 No 0
USP25-005 ENSP00000404086
ENST00000453553
Show » 204 23.6 No 0
USP25-006 ENSP00000402354
ENST00000449491
229 26.8 No 0
USP25-201 ENSP00000383044
ENST00000400183
Q9UHP3
Show all »
Show » Show » 1125 130 No 0