FZD7

GENE INFORMATION

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Gene name

FZD7 (HGNC Symbol)

Synonyms

FzE3

Description

frizzled family receptor 7 (HGNC Symbol)

Entrez gene summary

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q33.1

Chromosome location (bp)

202899310 - 202903160

Ensembl

ENSG00000155760 (version 73.37)

Entrez gene

8324

UniProt

O75084 (UniProt - Evidence at transcript level)

neXtProt

NX_O75084

Antibodypedia

FZD7 antibodies
 

PROTEIN VIEW

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FZD7-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FZD7-001 ENSP00000286201
ENST00000286201
O75084
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