ADK

GENE INFORMATION

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Gene name

ADK (HGNC Symbol)

Synonyms

AK

Description

adenosine kinase (HGNC Symbol)

Entrez gene summary

This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

Chromosome

10 (Chromosome progress)

Cytoband

q22.2

Chromosome location (bp)

75910960 - 76469061

Ensembl

ENSG00000156110 (version 73.37)

Entrez gene

132

UniProt

P55263 (UniProt - Evidence at protein level)

neXtProt

NX_P55263

Antibodypedia

ADK antibodies
 

PROTEIN VIEW

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ADK-001
 
ADK-003
 
ADK-201
 
ADK-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADK-001 ENSP00000286621
ENST00000286621
P55263
Show all »
Show » Show » 362 40.5 No 0
ADK-003 ENSP00000361819
ENST00000372734
P55263
Show all »
Show » Show » 345 38.7 No 0
ADK-201 ENSP00000443965
ENST00000539909
P55263
Show all »
Show » Show » 305 34.1 No 0
ADK-202 ENSP00000438321
ENST00000541550
P55263
Show all »
Show » Show » 327 36.6 No 0