ADAMTS3

GENE INFORMATION

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Gene name

ADAMTS3 (HGNC Symbol)

Synonyms

ADAMTS-4, KIAA0366

Description

ADAM metallopeptidase with thrombospondin type 1 motif, 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q13.3

Chromosome location (bp)

73146686 - 73434516

Ensembl

ENSG00000156140 (version 73.37)

Entrez gene

9508

UniProt

O15072 (UniProt - Evidence at transcript level)

neXtProt

NX_O15072

Antibodypedia

ADAMTS3 antibodies
 

PROTEIN VIEW

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ADAMTS3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAMTS3-001 ENSP00000286657
ENST00000286657
O15072
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