N6AMT1

GENERAL INFORMATION

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Gene name

N6AMT1

Gene description

N-6 adenine-specific DNA methyltransferase 1 (putative)

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic and nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
CAB034133 , CAB034135
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

N6AMT1 (HGNC Symbol)

Synonyms

C21orf127, HEMK2, MTQ2, N6AMT, PRED28

Description

N-6 adenine-specific DNA methyltransferase 1 (putative) (HGNC Symbol)

Entrez gene summary

This gene encodes an N(6)-adenine-specific DNA methyltransferase. The encoded enzyme may be involved in the methylation of release factor I during translation termination. This enzyme is also involved in converting the arsenic metabolite monomethylarsonous acid to the less toxic dimethylarsonic acid. Alternative splicing pf this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Jul 2014]

Chromosome

21

Cytoband

q21.3

Chromosome location (bp)

28872191 - 28885371

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000156239 (version 78.38)

Entrez gene

29104

UniProt

Q9Y5N5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5N5

Antibodypedia

N6AMT1 antibodies


PROTEIN BROWSER

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ENST00000303775
 
ENST00000351429
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

N6AMT1-001 ENSP00000303584
ENST00000303775
B2RA97
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Show » Show » 214 23 No 0
N6AMT1-002 ENSP00000286764
ENST00000351429
Q9Y5N5
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Show » Show » 186 19.8 No 0