PTDSS1

GENE INFORMATION

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Gene name

PTDSS1 (HGNC Symbol)

Synonyms

KIAA0024, PSS1, PSSA

Description

phosphatidylserine synthase 1 (HGNC Symbol)

Entrez gene summary

Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS1, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).[supplied by OMIM, May 2009]

Chromosome

8 (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

97273943 - 97349223

Ensembl

ENSG00000156471 (version 73.37)

Entrez gene

9791

UniProt

P48651 (UniProt - Evidence at protein level)

neXtProt

NX_P48651

Antibodypedia

PTDSS1 antibodies
 

PROTEIN VIEW

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PTDSS1-001
 
PTDSS1-002
 
PTDSS1-003
 
PTDSS1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PTDSS1-001 ENSP00000430548
ENST00000517309
P48651
Show all »
Show » Show » 473 55.5 No 9
PTDSS1-002 ENSP00000337331
ENST00000337004
J3KNR6
Show all »
Show » Show » 108 12.5 No 2
PTDSS1-003 ENSP00000430928
ENST00000522072
B4DE85
Show all »
Show » Show » 301 34.6 No 5
PTDSS1-201 ENSP00000401248
ENST00000455950
Q9BUQ5
Show all »
Show » Show » 327 38.3 No 6