Fields »

SUBCELLULAR LOCATION

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Main location(s)

Mitochondria

Additional location(s)

Nucleus but not nucleoli 

Staining summary

Mainly localized to mitochondria but also detected in the nucleus.

Reliability (APE)

High

Antibodies in assay

HPA007044, HPA011956
 

Antibody HPA007044

 

Antibody HPA011956

 

         Cell line A-431

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Location(s)

Mitochondria Nucleus but not nucleoli, Mitochondria 

Staining characteristics

 Granular 

Staining intensity

Moderate Moderate 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
The multi-targeting antibody yielding a staining pattern partly consistent with available gene/protein characterization data for all of the genes.
 

Comment

  

         Cell line U-2 OS

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Location(s)

Mitochondria Nucleus but not nucleoli, Mitochondria 

Staining characteristics

 Granular 

Staining intensity

Strong Moderate 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
The multi-targeting antibody yielding a staining pattern partly consistent with available gene/protein characterization data for all of the genes.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Mitochondria Nucleus but not nucleoli, Mitochondria 

Staining characteristics

  

Staining intensity

Strong Weak 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
The multi-targeting antibody yielding a staining pattern partly consistent with available gene/protein characterization data for all of the genes.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-2 OS shows positivity in mitochondria.
 

Immunofluorescent staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli & mitochondria.
 

Summary

Staining of mitochondria in all three cell lines.   Staining of mitochondria and nucleus in all three cell lines.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is supported by literature.
 

Dictionary

Mitochondria
Nucleus but not nucleoli