KAT6B

GENE INFORMATION

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Gene name

KAT6B (HGNC Symbol)

Synonyms

Morf, MOZ2, MYST4, qkf, querkopf, ZC2HC6B

Description

K(lysine) acetyltransferase 6B (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

Chromosome

10 (Chromosome progress)

Cytoband

q22.2

Chromosome location (bp)

76585340 - 76792380

Ensembl

ENSG00000156650 (version 73.37)

Entrez gene

23522

UniProt

Q8WYB5 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WYB5

Antibodypedia

KAT6B antibodies
 

PROTEIN VIEW

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KAT6B-001
 
KAT6B-002
 
KAT6B-003
 
KAT6B-004
 
KAT6B-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KAT6B-001 ENSP00000361809
ENST00000372724
Q8WYB5
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Show » Show » 1781 199.9 No 0
KAT6B-002 ENSP00000361810
ENST00000372725
Q8WYB5
Show all »
Show » Show » 1781 199.9 No 0
KAT6B-003 ENSP00000287239
ENST00000287239
Q8WYB5
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Show » Show » 2073 231.4 No 0
KAT6B-004 ENSP00000361796
ENST00000372711
Q8WYB5
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Show » Show » 1890 211.5 No 0
KAT6B-006 ENSP00000361799
ENST00000372714
Q8WYB5
Show all »
Show » Show » 1781 199.9 No 0