MAPK13

GENE INFORMATION

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Gene name

MAPK13 (HGNC Symbol)

Synonyms

p38delta, PRKM13, SAPK4

Description

Mitogen-activated protein kinase 13 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the mitogen-activated protein (MAP) kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The encoded protein is a p38 MAP kinase and is activated by proinflammatory cytokines and cellular stress. Substrates of the encoded protein include the transcription factor ATF2 and the microtubule dynamics regulator stathmin. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]

Chromosome

6

Cytoband

p21.31

Chromosome location (bp)

36095586 - 36107842

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000156711 (version 75.37)

Entrez gene

5603

UniProt

O15264 (UniProt - Evidence at protein level)

neXtProt

NX_O15264

Antibodypedia

MAPK13 antibodies
 

PROTEIN VIEW

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MAPK13-001
 
MAPK13-004
 
MAPK13-201
 
MAPK13-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAPK13-001 ENSP00000211287
ENST00000211287
O15264
Show all »
Show » Show » 365 42.1 No 0
MAPK13-004 ENSP00000362864
ENST00000373759
Q5R3E6
Show all »
Show » Show » 152 17.3 No 0
MAPK13-201 ENSP00000362866
ENST00000373761
Q5R3E4
Show all »
Show » Show » 355 41 No 0
MAPK13-202 ENSP00000362871
ENST00000373766
Q5U4A5
Show all »
Show » Show » 257 28.8 No 0