GPR112

GENE INFORMATION

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Gene name

GPR112 (HGNC Symbol)

Synonyms

PGR17, RP1-299I16

Description

G protein-coupled receptor 112 (HGNC Symbol)

Entrez gene summary

This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptor. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010]

Chromosome

X (Chromosome progress)

Cytoband

q26.3

Chromosome location (bp)

135383122 - 135519215

Ensembl

ENSG00000156920 (version 73.37)

Entrez gene

139378

UniProt

Q8IZF6 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8IZF6

Antibodypedia

GPR112 antibodies
 

PROTEIN VIEW

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GPR112-002
 
GPR112-003
 
GPR112-201
 
GPR112-202
 
GPR112-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPR112-002 ENSP00000377697
ENST00000394141
Q8IZF6
Show all »
Show » Show » 2875 309.4 No 7
GPR112-003 ENSP00000377699
ENST00000394143
Q8IZF6
Show all »
Show » Show » 3080 333.4 No 7
GPR112-201 ENSP00000287534
ENST00000287534
Q8IZF6
Show all »
Show » Show » 2804 301.6 No 7
GPR112-202 ENSP00000359686
ENST00000370652
Q8IZF6
Show all »
Show » Show » 3080 333.4 No 7
GPR112-203 ENSP00000416526
ENST00000412101
Q8IZF6
Show all »
Show » Show » 2875 309.4 No 7