BUB1B

GENE INFORMATION

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Gene name

BUB1B (HGNC Symbol)

Synonyms

Bub1A, BUBR1, MAD3L, SSK1

Description

BUB1 mitotic checkpoint serine/threonine kinase B (HGNC Symbol)

Entrez gene summary

This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q15.1

Chromosome location (bp)

40453224 - 40513337

Ensembl

ENSG00000156970 (version 73.37)

Entrez gene

701

UniProt

O60566 (UniProt - Evidence at protein level)

neXtProt

NX_O60566

Antibodypedia

BUB1B antibodies
 

PROTEIN VIEW

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BUB1B-001
 
BUB1B-003
 
BUB1B-005
 
BUB1B-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BUB1B-001 ENSP00000287598
ENST00000287598
O60566
Show all »
Show » Show » 1050 119.5 No 0
BUB1B-003 ENSP00000398470
ENST00000412359
O60566
Show all »
Show » Show » 1064 121.4 No 0
BUB1B-005 ENSP00000453643
ENST00000559733
Show » 66 7.2 No 0
BUB1B-011 ENSP00000453861
ENST00000558715
H0YN44
Show all »
Show » 96 10.4 No 0