SST

GENERAL INFORMATION

? »

Gene name

SST

Gene description

Somatostatin

Protein class

Cancer-related genes
Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Group enriched (cerebral cortex, duodenum, pancreas, small intestine, stomach)
GTEx:Tissue enhanced (pancreas, stomach)

Protein evidence

Evidence at protein level

Protein localization

Selective expression in islets of Langerhans and enteroendocrine cells in the gastrointestinal tract.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining consistent with RNA expression data.

Data reliability

Supportive based on 2 antibodies.
HPA019472 , CAB000075
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Group enriched (cerebral cortex, duodenum, pancreas, small intestine, stomach)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (pancreas, stomach)

Organ

Expression



GENE INFORMATION

? »

Gene name

SST (HGNC Symbol)

Synonyms

SMST

Description

Somatostatin (HGNC Symbol)

Entrez gene summary

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q27.3

Chromosome location (bp)

187668906 - 187670399

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000157005 (version 78.38)

Entrez gene

6750

UniProt

P61278 (UniProt - Evidence at protein level)

neXtProt

NX_P61278

Antibodypedia

SST antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000287641
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SST-001 ENSP00000287641
ENST00000287641
P61278
Show all »
Show » Show » 116 12.7 Yes 0