C8A

GENE INFORMATION

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Gene name

C8A

Synonyms

Description

complement component 8, alpha polypeptide (HGNC Symbol)

Entrez gene summary

C8 is a component of the complement system and contains three polypeptides, alpha, beta and gamma. This gene encodes the alpha subunit of C8. C8 participates in the formation of the membrane attack complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause complement C8 alpha-gamma deficiency. [provided by RefSeq, Nov 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p32.2

Chromosome location (bp)

57320479 - 57383894

Ensembl

ENSG00000157131 (version 73.37)

Entrez gene

731

UniProt

P07357 (UniProt - Evidence at protein level)

neXtProt

NX_P07357

Antibodypedia

C8A antibodies
 

PROTEIN VIEW

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C8A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

C8A-001 ENSP00000354458
ENST00000361249
P07357
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