CACNA1D

GENE INFORMATION

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Gene name

CACNA1D (HGNC Symbol)

Synonyms

CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2

Description

calcium channel, voltage-dependent, L type, alpha 1D subunit (HGNC Symbol)

Entrez gene summary

Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

Chromosome

3 (Chromosome progress)

Cytoband

p21.1

Chromosome location (bp)

53528683 - 53846490

Ensembl

ENSG00000157388 (version 73.37)

Entrez gene

776

UniProt

Q01668 (UniProt - Evidence at protein level)

neXtProt

NX_Q01668

Antibodypedia

CACNA1D antibodies
 

PROTEIN VIEW

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CACNA1D-001
 
CACNA1D-002
 
CACNA1D-003
 
CACNA1D-004
 
CACNA1D-007
 
CACNA1D-201
 
CACNA1D-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CACNA1D-001 ENSP00000288139
ENST00000288139
Q01668
Show all »
Show » Show » 2181 247.6 No >9
CACNA1D-002 ENSP00000409174
ENST00000422281
Q01668
Show all »
Show » Show » 2137 242.4 No >9
CACNA1D-003 ENSP00000288133
ENST00000350061
Q01668
Show all »
Show » Show » 2161 245.1 No >9
CACNA1D-004 ENSP00000418014
ENST00000481478
Q59GD8
Show all »
Show » Show » 1854 211.5 No >9
CACNA1D-007 ENSP00000418045
ENST00000481085
Show » Show » 264 30.3 No 3
CACNA1D-201 ENSP00000438229
ENST00000540742
F5H313
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Show » Show » 539 62.4 No 6
CACNA1D-202 ENSP00000440956
ENST00000544977
B7Z269
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351 40.4 No 0