CACNA2D3

GENE INFORMATION

? »

Gene name

CACNA2D3 (HGNC Symbol)

Synonyms

HSA272268

Description

calcium channel, voltage-dependent, alpha 2/delta subunit 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

p14.3

Chromosome location (bp)

54156574 - 55108584

Ensembl

ENSG00000157445 (version 73.37)

Entrez gene

55799

UniProt

Q8IZS8 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IZS8

Antibodypedia

CACNA2D3 antibodies
 

PROTEIN VIEW

? »
 
 
 
CACNA2D3-001
 
CACNA2D3-002
 
CACNA2D3-003
 
CACNA2D3-004
 
CACNA2D3-005
 
CACNA2D3-006
 
CACNA2D3-201
 
CACNA2D3-202
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CACNA2D3-001 ENSP00000419101
ENST00000474759
Q8IZS8
Show all »
Show » Show » 1091 123 Yes 2
CACNA2D3-002 ENSP00000417279
ENST00000490478
Q8IZS8
Show all »
Show » Show » 997 113 No 2
CACNA2D3-003 ENSP00000418228
ENST00000471363
Q8IZS8
Show all »
Show » Show » 519 59.5 No 0
CACNA2D3-004 ENSP00000417318
ENST00000477024
B4DSF6
Show all »
Show » 525 60.2 No 0
CACNA2D3-005 ENSP00000417455
ENST00000468658
F8WAV4
Show all »
46 5.3 No 0
CACNA2D3-006 ENSP00000418028
ENST00000492460
C9JAV5
Show all »
Show » 126 14.6 No 0
CACNA2D3-201 ENSP00000288197
ENST00000288197
Q8IZS8
Show all »
Show » Show » 1091 123 Yes 2
CACNA2D3-202 ENSP00000389506
ENST00000415676
Q8IZS8
Show all »
Show » Show » 1091 123 Yes 2