KCNJ6

GENE INFORMATION

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Gene name

KCNJ6 (HGNC Symbol)

Synonyms

BIR1, GIRK2, hiGIRK2, KATP2, KCNJ7, Kir3.2

Description

potassium inwardly-rectifying channel, subfamily J, member 6 (HGNC Symbol)

Entrez gene summary

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq, Jul 2008]

Chromosome

21 (Chromosome progress)

Cytoband

q22.13

Chromosome location (bp)

38996789 - 39288749

Ensembl

ENSG00000157542 (version 73.37)

Entrez gene

3763

UniProt

P48051 (UniProt - Evidence at protein level)

neXtProt

NX_P48051

Antibodypedia

KCNJ6 antibodies
 

PROTEIN VIEW

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KCNJ6-001
 
KCNJ6-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNJ6-001 ENSP00000383330
ENST00000400482
P48051
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Show » Show » 423 48.5 No 2
KCNJ6-201 ENSP00000288309
ENST00000288309
P48051
Show all »
Show » Show » 423 48.5 No 2