ACAN

GENE INFORMATION

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Gene name

ACAN (HGNC Symbol)

Synonyms

AGC1, CSPG1, CSPGCP, MSK16

Description

aggrecan (HGNC Symbol)

Entrez gene summary

This gene is a member of the aggrecan/versican proteoglycan family. The encoded protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q26.1

Chromosome location (bp)

89346674 - 89418585

Ensembl

ENSG00000157766 (version 73.37)

Entrez gene

176

UniProt

neXtProt

Antibodypedia

ACAN antibodies
 

PROTEIN VIEW

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ACAN-001
 
ACAN-003
 
ACAN-004
 
ACAN-005
 
ACAN-006
 
ACAN-008
 
ACAN-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACAN-001 ENSP00000453003
ENST00000558207
Q6PID9
Show all »
Show » 721 79.6 Yes 0
ACAN-003 ENSP00000452682
ENST00000558704
156 17.3 No 0
ACAN-004 ENSP00000341615
ENST00000352105
E7ENV9
Show all »
Show » 2431 250.4 Yes 0
ACAN-005 ENSP00000453581
ENST00000560601
Q6LE94
Show all »
Show » 226 24.2 No 0
ACAN-006 ENSP00000453342
ENST00000561243
E7EX88
Show all »
Show » 2530 261.3 Yes 0
ACAN-008 ENSP00000453499
ENST00000559004
H0YM81
Show all »
Show » 2492 257.4 Yes 0
ACAN-201 ENSP00000387356
ENST00000439576
E7EX88
Show all »
Show » 2530 261.3 Yes 0