FANCC

GENE INFORMATION

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Gene name

FANCC (HGNC Symbol)

Synonyms

FA3, FAC, FACC

Description

Fanconi anemia, complementation group C (HGNC Symbol)

Entrez gene summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group C. [provided by RefSeq, Jul 2008]

Chromosome

9 (Chromosome progress)

Cytoband

q22.32

Chromosome location (bp)

97861336 - 98079991

Ensembl

ENSG00000158169 (version 73.37)

Entrez gene

2176

UniProt

Q00597 (UniProt - Evidence at protein level)

neXtProt

NX_Q00597

Antibodypedia

FANCC antibodies
 

PROTEIN VIEW

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FANCC-001
 
FANCC-002
 
FANCC-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FANCC-001 ENSP00000289081
ENST00000289081
Q00597
Show all »
Show » Show » 558 63.4 No 0
FANCC-002 ENSP00000364454
ENST00000375305
Q00597
Show all »
Show » Show » 558 63.4 No 0
FANCC-004 ENSP00000406908
ENST00000433829
B1ALR7
Show all »
Show » Show » 150 17.3 No 0