Fields »

SUBCELLULAR LOCATION

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Main location(s)

Nucleus but not nucleoli

Additional location(s)

Plasma membrane 

Staining summary

Mainly localized to the nucleus.

Reliability (APE)

Medium

Antibodies in assay

HPA011880, CAB017786
 

Antibody HPA011880

 

Antibody CAB017786

 

         Cell line A-431

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Location(s)

Nucleus but not nucleoli, Plasma membrane  

Staining characteristics

  

Staining intensity

Moderate Negative 

Validation

Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Cell line U-2 OS

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Location(s)

Nucleus but not nucleoli  

Staining characteristics

  

Staining intensity

Moderate Negative 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Nucleus but not nucleoli  

Staining characteristics

Smooth  

Staining intensity

Moderate Negative 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
No staining.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli.
 

Immunofluorescent staining of human cell line U-2 OS shows no positivity.
 

Summary

Staining of nucleus but not nucleoli i all three cell lines with additional staining of plasma membrane in A-431.   No staining was observed in any of the three cell lines.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Nucleus but not nucleoli
Plasma membrane