GPRASP2

GENERAL INFORMATION

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Gene name

GPRASP2

Gene description

G protein-coupled receptor associated sorting protein 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues showed weak to moderate cytoplasmic staining occasionally combined with nuclear positivity. Strong immunoreactivity was observed in respiratory epithelium, glandular cells in thyroid, squamous epithelia and neuronal cells in CNS. Lung, gastrointestinal tract, glial cells and spleen were negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA017438
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

GPRASP2 (HGNC Symbol)

Synonyms

FLJ37327, GASP2

Description

G protein-coupled receptor associated sorting protein 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of a family that regulates the activity of G protein-coupled receptors (GPCRs). The encoded protein has been shown to be capable of interacting with several GPCRs, including the M1 muscarinic acetylcholine receptor and the calcitonin receptor. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

Chromosome

X

Cytoband

q22.1

Chromosome location (bp)

102712176 - 102717733

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158301 (version 78.38)

Entrez gene

114928

UniProt

Q96D09 (UniProt - Evidence at protein level)

neXtProt

NX_Q96D09

Antibodypedia

GPRASP2 antibodies


PROTEIN BROWSER

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ENST00000332262
 
ENST00000535209
 
ENST00000543253
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPRASP2-001 ENSP00000339057
ENST00000332262
Q96D09
Show all »
Show » Show » 838 93.8 No 0
GPRASP2-201 ENSP00000437394
ENST00000535209
Q96D09
Show all »
Show » Show » 838 93.8 No 0
GPRASP2-202 ENSP00000437872
ENST00000543253
Q96D09
Show all »
Show » Show » 838 93.8 No 0