KCNB1

GENE INFORMATION

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Gene name

KCNB1 (HGNC Symbol)

Synonyms

Kv2.1

Description

potassium voltage-gated channel, Shab-related subfamily, member 1 (HGNC Symbol)

Entrez gene summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]

Chromosome

20 (Chromosome progress)

Cytoband

q13.13

Chromosome location (bp)

47980414 - 48099184

Ensembl

ENSG00000158445 (version 73.37)

Entrez gene

3745

UniProt

Q14721 (UniProt - Evidence at protein level)

neXtProt

NX_Q14721

Antibodypedia

KCNB1 antibodies
 

PROTEIN VIEW

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KCNB1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNB1-001 ENSP00000360806
ENST00000371741
Q14721
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