CD1D

GENE INFORMATION

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Gene name

CD1D

Synonyms

Description

CD1d molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q23.1

Chromosome location (bp)

158149737 - 158154686

Ensembl

ENSG00000158473 (version 73.37)

Entrez gene

912

UniProt

P15813 (UniProt - Evidence at protein level)

neXtProt

NX_P15813

Antibodypedia

CD1D antibodies
 

PROTEIN VIEW

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CD1D-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD1D-001 ENSP00000357153
ENST00000368171
P15813
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