CD1A

GENE INFORMATION

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Gene name

CD1A (HGNC Symbol)

Synonyms

CD1

Description

CD1a molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q23.1

Chromosome location (bp)

158223927 - 158228059

Ensembl

ENSG00000158477 (version 73.37)

Entrez gene

909

UniProt

P06126 (UniProt - Evidence at protein level)

neXtProt

NX_P06126

Antibodypedia

CD1A antibodies
 

PROTEIN VIEW

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CD1A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD1A-001 ENSP00000289429
ENST00000289429
P06126
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