CD1C

GENE INFORMATION

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Gene name

CD1C (HGNC Symbol)

Synonyms

CD1

Description

CD1c molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

q23.1

Chromosome location (bp)

158259576 - 158263420

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158481 (version 75.37)

Entrez gene

911

UniProt

P29017 (UniProt - Evidence at protein level)

neXtProt

NX_P29017

Antibodypedia

CD1C antibodies
 

PROTEIN VIEW

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CD1C-001
 
CD1C-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD1C-001 ENSP00000357152
ENST00000368170
P29017
Show all »
Show » Show » 333 37.7 Yes 1
CD1C-003 ENSP00000408755
ENST00000443761
Show » Show » 281 31.6 No 0