CD1B

GENE INFORMATION

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Gene name

CD1B (HGNC Symbol)

Synonyms

CD1

Description

CD1b molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q23.1

Chromosome location (bp)

158297741 - 158301321

Ensembl

ENSG00000158485 (version 73.37)

Entrez gene

910

UniProt

P29016 (UniProt - Evidence at protein level)

neXtProt

NX_P29016

Antibodypedia

CD1B antibodies
 

PROTEIN VIEW

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CD1B-001
 
CD1B-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD1B-001 ENSP00000357150
ENST00000368168
P29016
Show all »
Show » Show » 333 36.9 Yes 1
CD1B-002 ENSP00000395161
ENST00000451207
Show » 246 27.1 No 1