CD1E

GENE INFORMATION

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Gene name

CD1E

Synonyms

Description

CD1e molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined. [provided by RefSeq, Jun 2010]

Chromosome

1 (Chromosome progress)

Cytoband

q23.1

Chromosome location (bp)

158323254 - 158327343

Ensembl

ENSG00000158488 (version 73.37)

Entrez gene

913

UniProt

P15812 (UniProt - Evidence at protein level)

neXtProt

NX_P15812

Antibodypedia

CD1E antibodies
 

PROTEIN VIEW

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 « 
 
CD1E-001
 
CD1E-002
 
CD1E-003
 
CD1E-004
 
CD1E-005
 
CD1E-006
 
CD1E-007
 
CD1E-008
 
CD1E-009
 
CD1E-010
 
CD1E-011
 
CD1E-012
 
CD1E-013
 
CD1E-201
 
CD1E-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD1E-001 ENSP00000357149
ENST00000368167
P15812
Show all »
Show » Show » 388 43.6 Yes 1
CD1E-002 ENSP00000357139
ENST00000368157
P15812
Show all »
Show » Show » 132 15 Yes 1
CD1E-003 ENSP00000416228
ENST00000452291
P15812
Show all »
Show » Show » 199 22.3 Yes 1
CD1E-004 ENSP00000357148
ENST00000368166
P15812
Show all »
Show » Show » 187 21 Yes 1
CD1E-005 ENSP00000357142
ENST00000368160
P15812
Show all »
Show » Show » 376 42.3 Yes 1
CD1E-006 ENSP00000357143
ENST00000368161
P15812
Show all »
Show » Show » 290 32.7 Yes 0
CD1E-007 ENSP00000357145
ENST00000368163
P15812
Show all »
Show » Show » 321 36.4 Yes 1
CD1E-008 ENSP00000357147
ENST00000368165
P15812
Show all »
Show » Show » 298 33.6 Yes 1
CD1E-009 ENSP00000357138
ENST00000368156
P15812
Show all »
Show » Show » 286 32.3 Yes 1
CD1E-010 ENSP00000357137
ENST00000368155
P15812
Show all »
Show » Show » 231 26.3 Yes 1
CD1E-011 ENSP00000357146
ENST00000368164
P15812
Show all »
Show » Show » 101 11.4 Yes 0
CD1E-012 ENSP00000357136
ENST00000368154
P15812
Show all »
Show » Show » 144 16.3 Yes 1
CD1E-013 ENSP00000357144
ENST00000368162
60 6.9 No 0
CD1E-201 ENSP00000401957
ENST00000434258
E7ET31
Show all »
Show » Show » 340 38.5 No 1
CD1E-202 ENSP00000402906
ENST00000444681
P15812
Show all »
Show » Show » 289 32.3 Yes 1