MRPL10

GENE INFORMATION

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Gene name

MRPL10 (HGNC Symbol)

Synonyms

L10MT, MGC17973, MRP-L10, MRP-L8, MRPL8, RPML8

Description

mitochondrial ribosomal protein L10 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010]

Chromosome

17 (Chromosome progress)

Cytoband

q21.32

Chromosome location (bp)

45900638 - 45908900

Ensembl

ENSG00000159111 (version 73.37)

Entrez gene

124995

UniProt

Q7Z7H8 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z7H8

Antibodypedia

MRPL10 antibodies
 

PROTEIN VIEW

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MRPL10-001
 
MRPL10-002
 
MRPL10-003
 
MRPL10-004
 
MRPL10-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL10-001 ENSP00000324100
ENST00000351111
Q7Z7H8
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Show » Show » 261 29.3 No 0
MRPL10-002 ENSP00000395870
ENST00000414011
Q7Z7H8
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Show » Show » 271 30.3 No 0
MRPL10-003 ENSP00000290208
ENST00000290208
Q7Z7H8
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Show » Show » 271 30.3 No 0
MRPL10-004 ENSP00000404039
ENST00000421763
F2Z2K7
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48 5.1 No 0
MRPL10-006 ENSP00000390624
ENST00000423147
F2Z2K7
Show all »
48 5.1 No 0