GART

GENE INFORMATION

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Gene name

GART (HGNC Symbol)

Synonyms

PGFT, PRGS

Description

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a trifunctional polypeptide. It has phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase activity which is required for de novo purine biosynthesis. This enzyme is highly conserved in vertebrates. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

21 (Chromosome progress)

Cytoband

q22.11

Chromosome location (bp)

34876238 - 34915797

Ensembl

ENSG00000159131 (version 73.37)

Entrez gene

2618

UniProt

P22102 (UniProt - Evidence at protein level)

neXtProt

NX_P22102

Antibodypedia

GART antibodies
 

PROTEIN VIEW

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GART-001
 
GART-002
 
GART-003
 
GART-004
 
GART-006
 
GART-007
 
GART-008
 
GART-009
 
GART-010
 
GART-014
 
GART-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GART-001 ENSP00000371253
ENST00000381831
P22102
Show all »
Show » Show » 1010 107.8 No 0
GART-002 ENSP00000390003
ENST00000424203
F8WD69
Show all »
Show » 306 32.3 No 0
GART-003 ENSP00000371236
ENST00000381815
P22102
Show all »
Show » Show » 1010 107.8 No 0
GART-004 ENSP00000354388
ENST00000361093
P22102
Show all »
Show » Show » 433 46 No 0
GART-006 ENSP00000371261
ENST00000381839
P22102
Show all »
Show » Show » 1010 107.8 No 0
GART-007 ENSP00000413040
ENST00000430874
C9JTV6
Show all »
Show » 241 25.2 No 0
GART-008 ENSP00000413803
ENST00000438059
C9JKQ7
Show all »
Show » 138 14.7 No 0
GART-009 ENSP00000398631
ENST00000426819
C9JBJ1
Show all »
Show » 232 24.3 No 0
GART-010 ENSP00000407783
ENST00000441403
C9JZG2
Show all »
Show » 136 14.5 No 0
GART-014 ENSP00000409771
ENST00000366093
145 15 No 0
GART-201 ENSP00000443579
ENST00000543717
B4DJ93
Show all »
Show » Show » 562 60.2 No 0