ACTC1

GENE INFORMATION

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Gene name

ACTC1 (HGNC Symbol)

Synonyms

ACTC, CMD1R

Description

actin, alpha, cardiac muscle 1 (HGNC Symbol)

Entrez gene summary

Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC). [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q14

Chromosome location (bp)

35080297 - 35088340

Ensembl

ENSG00000159251 (version 73.37)

Entrez gene

70

UniProt

P68032 (UniProt - Evidence at protein level)

neXtProt

NX_P68032

Antibodypedia

ACTC1 antibodies
 

PROTEIN VIEW

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ACTC1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACTC1-001 ENSP00000290378
ENST00000290378
P68032
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