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SUBCELLULAR LOCATION

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Main location(s)

Cytoplasm, Cytoskeleton (Actin filaments)

Additional location(s)

 

Staining summary

Localized to actin filaments.

Reliability (APE)

Medium

Antibodies in assay

CAB003761, HPA041264
 

Antibody CAB003761

 

Antibody HPA041264

 

         Cell line A-431

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Location(s)

Cytoskeleton (Actin filaments)  

Staining characteristics

  

Staining intensity

Weak Negative 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
The multi-targeting antibody not yielding a staining pattern.
 

Comment

  

         Cell line U-2 OS

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Location(s)

Cytoskeleton (Actin filaments)  

Staining characteristics

  

Staining intensity

Weak Negative 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
The multi-targeting antibody not yielding a staining pattern.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Cytoskeleton (Actin filaments)  

Staining characteristics

Granular  

Staining intensity

Weak Negative 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
The multi-targeting antibody not yielding a staining pattern.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-2 OS shows positivity in cytoskeleton (actin filaments).
 

Immunofluorescent staining of human cell line A-431 shows no positivity.
 

Summary

Staining of cytoskeleton (actin filaments) in all three cell lines.   No staining was observed in any of the three cell lines.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is partly supported by literature or no literature is available.
 

Dictionary

Cytoplasm
Actin filaments