PSMB4

GENE INFORMATION

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Gene name

PSMB4 (HGNC Symbol)

Synonyms

HN3, PROS26

Description

proteasome (prosome, macropain) subunit, beta type, 4 (HGNC Symbol)

Entrez gene summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q21.3

Chromosome location (bp)

151372010 - 151374420

Ensembl

ENSG00000159377 (version 73.37)

Entrez gene

5692

UniProt

P28070 (UniProt - Evidence at protein level)

neXtProt

NX_P28070

Antibodypedia

PSMB4 antibodies
 

PROTEIN VIEW

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PSMB4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMB4-001 ENSP00000290541
ENST00000290541
P28070
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