CELF3

GENERAL INFORMATION

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Gene name

CELF3

Gene description

CUGBP, Elav-like family member 3

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (adrenal gland, cerebral cortex)
GTEx:Group enriched (cerebellum, cerebral cortex, hippocampus)

Protein evidence

Evidence at protein level

Protein localization

Weak to moderate cytoplasmic staining in most normal tissues. Additional nuclear staining in several tissues. Parathyroid gland showed luminal membranous staining. Alveolar cells, pancreatic islets, squamous epithelia and lymphoid tissues were in many cases negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA006292
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (adrenal gland, cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebellum, cerebral cortex, hippocampus)

Organ

Expression



GENE INFORMATION

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Gene name

CELF3 (HGNC Symbol)

Synonyms

BRUNOL1, CAGH4, ERDA4, MGC57297, TNRC4

Description

CUGBP, Elav-like family member 3 (HGNC Symbol)

Entrez gene summary

Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]

Chromosome

1

Cytoband

q21.3

Chromosome location (bp)

151702404 - 151716814

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000159409 (version 78.38)

Entrez gene

11189

UniProt

Q5SZQ8 (UniProt - Evidence at protein level)

neXtProt

NX_Q5SZQ8

Antibodypedia

CELF3 antibodies


PROTEIN BROWSER

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ENST00000290583
 
ENST00000290585
 
ENST00000420342
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CELF3-001 ENSP00000290583
ENST00000290583
Q5SZQ8
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Show » Show » 465 50.5 No 0
CELF3-002 ENSP00000290585
ENST00000290585
Q5SZQ8
Show all »
Show » Show » 415 45.7 No 0
CELF3-003 ENSP00000402503
ENST00000420342
B4DQL3
Show all »
Show » Show » 466 50.3 No 0