AMFR

GENE INFORMATION

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Gene name

AMFR (HGNC Symbol)

Synonyms

gp78, RNF45

Description

autocrine motility factor receptor, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins. [provided by RefSeq, Feb 2012]

Chromosome

16 (Chromosome progress)

Cytoband

q12.2

Chromosome location (bp)

56395364 - 56459450

Ensembl

ENSG00000159461 (version 73.37)

Entrez gene

267

UniProt

Q9UKV5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKV5

Antibodypedia

AMFR antibodies
 

PROTEIN VIEW

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AMFR-001
 
AMFR-002
 
AMFR-005
 
AMFR-007
 
AMFR-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AMFR-001 ENSP00000290649
ENST00000290649
Q9UKV5
Show all »
Show » Show » 643 73 Yes 6
AMFR-002 ENSP00000473636
ENST00000492830
R4GNG2
Show all »
Show » 299 33.9 No 0
AMFR-005 ENSP00000456745
ENST00000565445
H3BSK3
Show all »
Show » Show » 229 26.8 No 7
AMFR-007 ENSP00000455842
ENST00000563664
H3BQM3
Show all »
Show » Show » 165 19 No 4
AMFR-009 ENSP00000456288
ENST00000567738
H3BRK9
Show all »
Show » Show » 288 32.8 No 0