ATP6V0D1

GENERAL INFORMATION

? »

Gene name

ATP6V0D1

Gene description

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1

Protein class

Plasma proteins
Predicted intracellular proteins
Transporters

Predicted localization

Intracellular

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

A majority of the normal tissues showed weak to moderate cytoplasmic and membranous positivity. Renal tubular secretions and goblet cells in the intestine were distinctly stained. Squamous epithelia, hepatocytes, lymphoid tissues and neuronal tissues were weakly stained or negative.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA016938
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

ATP6V0D1 (HGNC Symbol)

Synonyms

ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD

Description

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 (HGNC Symbol)

Entrez gene summary

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q22.1

Chromosome location (bp)

67438014 - 67481237

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000159720 (version 78.38)

Entrez gene

9114

UniProt

P61421 (UniProt - Evidence at protein level)

neXtProt

NX_P61421

Antibodypedia

ATP6V0D1 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000290949
 
ENST00000540149
 
ENST00000564615
 
ENST00000565835
 
ENST00000602876
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP6V0D1-001 ENSP00000290949
ENST00000290949
P61421
Show all »
Show » Show » 351 40.3 No 0
ATP6V0D1-002 ENSP00000441282
ENST00000540149
F5GYQ1
Show all »
Show » Show » 392 44.7 No 0
ATP6V0D1-015 ENSP00000463328
ENST00000565835
Show » 232 26.7 No 0
ATP6V0D1-017 ENSP00000455802
ENST00000564615
Show » 227 25.5 No 0
ATP6V0D1-201 ENSP00000473515
ENST00000602876
R4GN72
Show all »
Show » Show » 274 31.7 No 0