ATP6V0D1

GENE INFORMATION

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Gene name

ATP6V0D1 (HGNC Symbol)

Synonyms

ATP6D, ATP6DV, P39, VATX, Vma6, VPATPD

Description

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 (HGNC Symbol)

Entrez gene summary

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. [provided by RefSeq, Jul 2008]

Chromosome

16 (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

67471917 - 67515140

Ensembl

ENSG00000159720 (version 73.37)

Entrez gene

9114

UniProt

P61421 (UniProt - Evidence at protein level)

neXtProt

NX_P61421

Antibodypedia

ATP6V0D1 antibodies
 

PROTEIN VIEW

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 « 
 
ATP6V0D1-001
 
ATP6V0D1-002
 
ATP6V0D1-004
 
ATP6V0D1-007
 
ATP6V0D1-008
 
ATP6V0D1-009
 
ATP6V0D1-010
 
ATP6V0D1-014
 
ATP6V0D1-015
 
ATP6V0D1-016
 
ATP6V0D1-017
 
ATP6V0D1-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP6V0D1-001 ENSP00000290949
ENST00000290949
P61421
Show all »
Show » Show » 351 40.3 No 0
ATP6V0D1-002 ENSP00000441282
ENST00000540149
F5GYQ1
Show all »
Show » Show » 392 44.7 No 0
ATP6V0D1-004 ENSP00000393910
ENST00000426604
58 6.3 No 0
ATP6V0D1-007 ENSP00000457105
ENST00000563064
H3BTB5
Show all »
Show » 57 6.2 No 0
ATP6V0D1-008 ENSP00000456695
ENST00000564191
H3BSG7
Show all »
Show » 115 13.1 No 0
ATP6V0D1-009 ENSP00000455446
ENST00000566322
71 7.9 No 0
ATP6V0D1-010 ENSP00000457104
ENST00000568101
40 4.1 No 0
ATP6V0D1-014 ENSP00000457744
ENST00000561852
H3BUQ0
Show all »
Show » 47 5.3 No 0
ATP6V0D1-015 ENSP00000463328
ENST00000565835
232 26.7 No 0
ATP6V0D1-016 ENSP00000455695
ENST00000564788
H3BQB4
Show all »
Show » 113 12.9 No 0
ATP6V0D1-017 ENSP00000455802
ENST00000564615
227 25.5 No 0
ATP6V0D1-201 ENSP00000473515
ENST00000602876
R4GN72
Show all »
274 31.7 No 0