AGRP

GENE INFORMATION

? »

Gene name

AGRP (HGNC Symbol)

Synonyms

Agrt, ART, ASIP2

Description

agouti related protein homolog (mouse) (HGNC Symbol)

Entrez gene summary

This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]

Chromosome

16 (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

67516474 - 67517716

Ensembl

ENSG00000159723 (version 73.37)

Entrez gene

181

UniProt

O00253 (UniProt - Evidence at protein level)

neXtProt

NX_O00253

Antibodypedia

AGRP antibodies
 

PROTEIN VIEW

? »
 
 
 
AGRP-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGRP-001 ENSP00000290953
ENST00000290953
O00253
Show all »
Show » Show » 132 14.4 Yes 0