ANKLE1

GENERAL INFORMATION

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Gene name

ANKLE1

Gene description

Ankyrin repeat and LEM domain containing 1

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (bone marrow)
GTEx:Tissue enhanced (cerebellum)

Protein evidence

Evidence at transcript level

Protein localization

RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA026789
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (bone marrow)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebellum)

Organ

Expression



GENE INFORMATION

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Gene name

ANKLE1 (HGNC Symbol)

Synonyms

ANKRD41, FLJ39369, LEMD6

Description

Ankyrin repeat and LEM domain containing 1 (HGNC Symbol)

Entrez gene summary

Chromosome

19

Cytoband

p13.11

Chromosome location (bp)

17281645 - 17287646

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000160117 (version 78.38)

Entrez gene

126549

UniProt

Q8NAG6 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8NAG6

Antibodypedia

ANKLE1 antibodies


PROTEIN BROWSER

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ENST00000394458
 
ENST00000594072
 
ENST00000598347
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANKLE1-001 ENSP00000468845
ENST00000594072
M0QX15
Show all »
Show » Show » 593 64 No 0
ANKLE1-003 ENSP00000377971
ENST00000394458
Q8NAG6
Show all »
Show » Show » 669 72.4 No 0
ANKLE1-006 ENSP00000470895
ENST00000598347
M0R002
Show all »
Show » Show » 598 64.2 No 1