KALRN

GENE INFORMATION

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Gene name

KALRN (HGNC Symbol)

Synonyms

ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD

Description

kalirin, RhoGEF kinase (HGNC Symbol)

Entrez gene summary

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q21.1

Chromosome location (bp)

123798870 - 124440036

Ensembl

ENSG00000160145 (version 73.37)

Entrez gene

8997

UniProt

O60229 (UniProt - Evidence at protein level)

neXtProt

NX_O60229

Antibodypedia

KALRN antibodies
 

PROTEIN VIEW

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 « 
 
KALRN-001
 
KALRN-002
 
KALRN-003
 
KALRN-004
 
KALRN-005
 
KALRN-009
 
KALRN-010
 
KALRN-013
 
KALRN-014
 
KALRN-016
 
KALRN-201
 
KALRN-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KALRN-001 ENSP00000291478
ENST00000291478
O60229
Show all »
Show » Show » 1289 144.5 No 0
KALRN-002 ENSP00000377134
ENST00000393496
O60229
Show all »
Show » Show » 738 82.8 No 0
KALRN-003 ENSP00000400064
ENST00000454902
C9J1B4
Show all »
194 21.1 No 0
KALRN-004 ENSP00000346122
ENST00000354186
Show » Show » 2955 336.2 No 0
KALRN-005 ENSP00000240874
ENST00000240874
O60229
Show all »
Show » Show » 1663 192.2 No 0
KALRN-009 ENSP00000402950
ENST00000439170
H7C1X7
Show all »
Show » 215 24.8 No 0
KALRN-010 ENSP00000395236
ENST00000448253
268 30.5 No 0
KALRN-013 ENSP00000418611
ENST00000460856
C9IZQ6
Show all »
Show » 1654 191.2 No 0
KALRN-014 ENSP00000420318
ENST00000459915
E7EUZ8
Show all »
Show » Show » 489 55.7 No 0
KALRN-016 ENSP00000418790
ENST00000462213
C9IYX8
Show all »
Show » 123 13.6 No 0
KALRN-201 ENSP00000353109
ENST00000360013
J3QSW6
Show all »
Show » Show » 2986 340.3 No 1
KALRN-202 ENSP00000402419
ENST00000428018
O60229
Show all »
Show » Show » 1257 141.2 No 0