IKZF3

GENE INFORMATION

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Gene name

IKZF3 (HGNC Symbol)

Synonyms

Aiolos, ZNFN1A3

Description

IKAROS family zinc finger 3 (Aiolos) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]

Chromosome

17 (Chromosome progress)

Cytoband

q12

Chromosome location (bp)

37921198 - 38020441

Ensembl

ENSG00000161405 (version 73.37)

Entrez gene

22806

UniProt

Q9UKT9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UKT9

Antibodypedia

IKZF3 antibodies
 

PROTEIN VIEW

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IKZF3-001
 
IKZF3-002
 
IKZF3-003
 
IKZF3-004
 
IKZF3-005
 
IKZF3-006
 
IKZF3-007
 
IKZF3-008
 
IKZF3-009
 
IKZF3-010
 
IKZF3-011
 
IKZF3-012
 
IKZF3-013
 
IKZF3-014
 
IKZF3-015
 
IKZF3-016
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IKZF3-001 ENSP00000344544
ENST00000346872
Q9UKT9
Show all »
Show » Show » 509 58 No 0
IKZF3-002 ENSP00000403776
ENST00000439167
Q9UKT9
Show all »
Show » Show » 436 49.8 No 0
IKZF3-003 ENSP00000345622
ENST00000351680
Q9UKT9
Show all »
Show » Show » 470 53.4 No 0
IKZF3-004 ENSP00000341977
ENST00000346243
Q9UKT9
Show all »
Show » Show » 431 49.1 No 0
IKZF3-005 ENSP00000344471
ENST00000350532
Q9UKT9
Show all »
Show » Show » 470 53.7 No 0
IKZF3-006 ENSP00000420463
ENST00000467757
Q9UKT9
Show all »
Show » Show » 453 51.6 No 0
IKZF3-007 ENSP00000463505
ENST00000348427
Q9UKT9
Show all »
Show » Show » 207 23.6 No 0
IKZF3-008 ENSP00000462791
ENST00000293068
Q9UKT9
Show all »
Show » Show » 263 30 No 0
IKZF3-009 ENSP00000367180
ENST00000377945
Q9UKT9
Show all »
Show » Show » 375 42.7 No 0
IKZF3-010 ENSP00000377741
ENST00000394189
Q9UKT9
Show all »
Show » Show » 327 36.9 No 0
IKZF3-011 ENSP00000367179
ENST00000377944
Q9UKT9
Show all »
Show » Show » 366 41.6 No 0
IKZF3-012 ENSP00000367194
ENST00000377958
Q9UKT9
Show all »
Show » Show » 422 48 No 0
IKZF3-013 ENSP00000438972
ENST00000535189
Q9UKT9
Show all »
Show » Show » 475 54.4 No 0
IKZF3-014 ENSP00000367188
ENST00000377952
Q9UKT9
Show all »
Show » Show » 288 32.7 No 0
IKZF3-015 ENSP00000403027
ENST00000439016
Q9UKT9
Show all »
Show » Show » 414 47 No 0
IKZF3-016 ENSP00000462452
ENST00000583368
B4DVV5
Show all »
Show » Show » 262 30 No 0